[Left-sided gallbladder and hypoplasia of the right hepatic lobe--a rare congenital anomaly]
Stankovic N. Petrovic M. Kostic Z.
Ectopic gallbladder, followed by other abnormalities in the anatomy of liver, biliary-pancreatic system, and portal vein is very rare congenital defect. The patient with left-sided gallbladder, complicated chronic calculous cholecystitis and hypoplasia of the right lobe of liver was presented. The diagnosis of this abnormality was confirmed intraoperatively. After cholecystectomy, postoperative course in the patient was uneventful.
[Chronic persistent hepatitis with an atypical clinical course]
Roganovic B. Milutinovic C. Usaj S.
Chronic persistent hepatitis is a form of chronic hepatitis with mild clinical course that does not require specific therapy. Diagnosis is established by liver biopsy. A 65 years old female patient, was admitted to the Clinic of gastroenterology with clinical and laboratory picture of obstructive jaundice with progressive deterioration. Obstruction was not found through performed examinations (US, CT, gastroduodenoscopy, ERCP). Viral liver infections as well as primary biliary cirrhosis were also excluded. Ultrasonically guided liver biopsy verified chronic persistent hepatitis. Specificity of this case was in atypical clinical course and treatment: obstructive jaundice clinical feature, rapid deterioration and corticosteroid treatment that led to the complete clinical and biochemical recovery.
Antiphospholipid antibodies in inflammatory bowel diseases.
Martinovic Z. Perisic K. Pejnovic N. Lukacevic S. Rabrenovic L. Petrovic M.
Military Medical Academy, Clinic for Gastroenterology, Belgrade.
Patients with inflammatory bowel diseases are susceptible to thrombosis in the active phase of the disease. Tests and some factors of coagulability have shown the existence of hypercoagulability of the blood in the active phase of these diseases. In the last few years some authors have found increased levels of antiphospholipid antibodies in the blood of patients with severe forms of Crohn's disease and ulcerative colitis. In a prospective study anticardiolipin antibodies have been measured in the blood of 12 patients, eight with ulcerative colitis and four with Crohn's disease. Six patients with ulcerative colitis and two with Crohn's disease were in the active phase of the disease, and the others in the remission. None of the patients had any clinical signs of thrombosis. Anticardiolipin antibodies were slightly increased in only one patient with severe ulcerative colitis complicated with erythema nodosum and swelling of the ankles. In nine patients anticardiolipin antibodies were in the normal range, but in two they were not found. Results of our study do not allow any definite conclusion regarding the possible role of antiphospholipid antibodies in the development of thrombosis in inflammatory bowel diseases: the number of the patients is relatively low and in half of the cases the disease was moderately active. Further studies are therefore necessary.