Mycoses

Disseminated Fusarium solani infection with endocarditis in a lung transplant recipient.

Year 1998
Guinvarc'h A. Guilbert L. Marmorat-Khuong A. Lavarde V. Chevalier P. Amrein C. Guillemain R. Berrebi A.
Department of Cardiovascular Surgery, Broussais Hospital, Paris, France.
Eleven days after double lung transplantation for cystic fibrosis, an 18-year-old patient developed a disseminated Fusarium solani infection with tricuspid valve endocarditis. This infection occurred under fluconazole and immunosuppressive therapy with cyclosporin, prednisone and azathioprine, with a normal leucocyte count. Liposomal amphotericin B allowed blood culture negativation. The patient died from a bacterial septic shock.