Fukuoka Igaku Zasshi

[Spontaneous regression of hepatocellular carcinoma: a case report]

Year 1998
Matsumata T. Takesue F. Suehiro T. Maeda T. Itasaka H. Yoshida K.
Department of Surgery, Saiseikai Yahata General Hospital (Kitakyushu).
A 65-year-old woman with hepatocellular carcinoma underwent right hepatic lobectomy. Her alpha-fetoprotein levels significantly dropped from 285,000 ng/ml to 3,100 ng/ml for one month without any preoperative treatment. The tumor thrombus in the portal vein showed complete necrosis, and lymphocytes infiltration around the main tumor were present microscopically. However, there was no necrotic area in the main tumor. This patient is living with no evidence of recurrence for 3 years and 6 months following hepatic resection.