Cervical spine involvement in metastatic colorectal carcinoma.
Geh JI. Glynne-Jones R.
Mount Vernon Hospital, Northwood, Middlesex, UK.
Bone metastasis in colorectal carcinoma is an uncommon occurrence. The lumbar and thoracic vertebrae are the most commonly reported sites. In contrast, the reported incidence of cervical vertebral involvement is relatively rare at 2%-7%. We document seven patients with colorectal carcinoma who presented with symptomatic cervical spine metastases and describe their clinical characteristics. This represents a disproportionately large number (24%) of those with bone metastases seen at this centre.
Intralesional interferon for the treatment of metastatic carcinoid tumours.
Schneider HJ. Heddle RM. Downes MO. Wan KM. Smedley HM.
The Kent and Canterbury Hospital, Canterbury, UK.
We report the first documented case of intralesional interferon administration for the palliation of carcinoid tumour metastases. This was performed under ultrasound guidance and gave a good clinical response, which correlated with tumour necrosis demonstrated by serial CT scanning.