Sleep in asthma.
D'Ambrosio CM. Mohsenin V.
Department of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
The nocturnal worsening of asthma is a major cause of morbidity and mortality from this disease. The physiologic changes that occur during normal sleep can have adverse effects on breathing patterns, arousal responses, and airway clearance in asthmatics. Understanding of these alterations in airway mechanics and airway inflammation may lead to better management of this disease.