[Prevalence of hepatitis C virus infection and cohabiting contacts]
Lopez Exposito F. Massague Camins C. Cano Romera A. Lopez Plana A. Espona Barris R. Lopez Martinez R.
Area Basica de Salud Bon Pastor, DAP Sant Andreu, Barcelona.
OBJECTIVES: Study of the prevalence of Hepatitis C infection and of cohabiting contacts. DESIGN: A descriptive crossover study. SETTING: Health District. PATIENTS: There were a total of 13,500 people with histories opened at our centre. The histories of patients attending for general medical consultations between January 1995 and December 1996 were reviewed for Ac+ to the Hepatitis C (HC) virus. RESULTS: 145 patients were found to be Ac positive for HC (1.07%; CI, 0.9-1.2). 135 were index cases and 10 contacts. The most important items of history were intravenous drug use in 33 carriers (23%), transfusion in 22 (15%), contact with non-disposable material in 97 (67%) and surgery in 119 (82%). 115 (79%) of those infected had Transaminase disorder (< x10). CONCLUSIONS: The 1.07% prevalence found was similar to other studies. Previous surgery stood out among the factors causing risk of infection. Prevalence among cohabitants was 7%, half through sexual contacts. Since there was a higher prevalence of HC+ among family members (50% sexual partners), we believe the study should be extended and followed up in the family environment.
[Evolution of the prevalence of hepatitis A antibody in Seville]
Rivera F. Ruiz J. Garcia de Pesquera F.
Hospital Universitario Virgen del Rocio Sevilla.
OBJECTIVE: To find the evolution of the prevalence of the Hepatitis-A antibody in Sevilla. DESIGN: Observational study of a crossover type. Comparison of results in 1995 with those from a similar study in 1981. SETTING: Health Area covered by Sevilla's University Hospital Virgen del Rocio. PATIENTS AND OTHER PARTICIPANTS: Aliquots of serum from patients without Hepatitis were obtained from the hospital's clinical analysis laboratories. MEASUREMENTS AND MAIN RESULTS: The sera were analysed in the Nuclear Medicine laboratory of the HUVR. 37.96% (62.74% in 1981) of the individuals surveyed were HA-positive. Prevalence increased with age: in the over-24s it was over 75% (90% in 1981). The differences between the two sets of results was significant (p < 0.001). CONCLUSIONS: Hepatitis-A infection is becoming less common in Andalusia, which can now be considered a low-incidence area.