Ann Acad Med Singapore

Imaging of thoracic manifestations of scleroderma.

Year 1998
Wong JS. Ng SC.
Department of Radiology, National University Hospital, Singapore.
Radiographs illustrating the various thoracic manifestations of systemic sclerosis are shown. These include pulmonary parenchymal disease e.g. interstitial pneumonitis and pneumonia, pleural disease (pneumothorax), cardiac involvement, oesophageal disease, bony changes and soft tissue calcification. The use of chest radiography and other imaging modalities such as high resolution computerised tomography (HRCT) of the thorax is discussed.

A case of sulindac-induced enteropathy resulting in jejunal perforation.

Year 1998
Yoon KH. Ng SC.
Department of Medicine, Alexandra Hospital, Singapore.
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely prescribed for rheumatic conditions. Their effects on the upper gastrointestinal tract are well recognised. Clinically important damage to the small intestines is less common and often unrecognised. We report a case of sulindac-induced jejunal perforation in a rheumatoid arthritis (RA) patient with previous gastrectomy for gastric carcinoma. The prevalence, diagnosis, pathogenesis and treatment options of NSAID-induced enteropathy will be discussed.